Virtual machines appeared as inaccessible in the vCenter UI.
Some VMs showed as running, but access to the web console was not possible.
Additionally, browsing files on the datastores was unsuccessful.
VMware vSphere ESXi(All Versions)
In var/run/log/vmkernel.log, triggers with "PDL and device is permanently unavailable"
2025-05-02T02:04:49.724Z cpu36:2098136)WARNING: NMP: nmp_PathDetermineFailure:3527: Cmd (0x2a) PDL error (0x5/0x25/0x0) - path vmhba1:C0:T14:L10 device naa.624a9370e84axxxxxxxxxxx - triggering path failover
2025-05-02T02:04:49.724Z cpu36:2098136)NMP: nmp_ThrottleLogForDevice:3867: Cmd 0x2a (0x45d9a53bdfc8, 2102896) to dev "naa.624a9370e84xxxxxxxxxxx" on path "vmhba1:C0:T14:L10" Failed:
2025-05-02T02:04:49.724Z cpu36:2098136)NMP: nmp_ThrottleLogForDevice:3875: H:0x0 D:0x2 P:0x0 Valid sense data: 0x5 0x25 0x0. Act:FAILOVER. cmdId.initiator=0x430d6821f580 CmdSN 0x8000002d
2025-05-02T02:04:50.700Z cpu17:2097624)VMW_SATP_ALUA: satp_alua_issueCommandOnPath:887: Path "vmhba2:C0:T18:L239" (PERM LOSS) command 0x12 failed with status Device is permanently unavailable. H:0x0 D:0x2 P:0x0 Valid sense data: 0x5 0x25 0x0.
2025-05-02T02:04:50.700Z cpu17:2097624)WARNING: VMW_SATP_ALUA: satp_alua_getTargetPortInfo:160: Could not get page 83 INQUIRY data for path "vmhba2:C0:T18:L239" - Device is permanently unavailable (195887410)
2025-05-02T02:04:50.700Z cpu17:2097624)VMW_SATP_ALUA: satp_alua_issueCommandOnPath:887: Path "vmhba1:C0:T8:L239" (PERM LOSS) command 0x12 failed with status Device is permanently unavailable. H:0x0 D:0x2 P:0x0 Valid sense data: 0x5 0x25 0x0.
2025-05-02T02:04:50.700Z cpu17:2097624)WARNING: VMW_SATP_ALUA: satp_alua_getTargetPortInfo:160: Could not get page 83 INQUIRY data for path "vmhba2:C0:T18:L239" - Device is in-accessible
In var/run/log/vobd.log there will be an error event with "lost connectivity to storage device"
2026-03-25T04:03:47.400Z: [scsiCorrelator] 19759076159151us:[vob. scsi. scsipath.pathstate.dead] scsiPath vmhbal:CO:T1:L2 changed state from on2026-03-25T04:03:47.401Z: esx.problem. storage. connectivity. lost] Lost connectivity to storage device naa.600009xxxxxxxxxxxxxxxxx. Path vmhbal:CO:TO:L3 is down. Affected datastores: "VOL_xxxxxxxxxxxxx"2026-03-25T04:03:47.401Z: [scsiCorrelator] 19758696379034us: [vob.scsi.scsipath.pathstate.dead] scsiPath vmhba0:CO:TO:L2 changed state from on2026-03-25T04:03:47.413Z: [scsiCorrelator] 19759076171858us: [esx.problem.scsi.device.state.permanentloss] Device: naa.600009xxxxxxxxxxxxxxxxx. has been removed or is permanently inaccessible. Affected datastores (if any): "VOL_xxxxxxxxxxxxx"