The ESXi host is very slow in responding to operations directed from the vCenter and the host UI.
On the ESXCLI window, commands ran to check the VMs processes, status of the management agents and logs will either be slow/unresponsive.
Commands to check performance esxtop or storage information runs well dmesg
VMware vSphere ESXi 7.x
The lun/datastore removed from the array might not be full detached leading the host searching for a lun that does not exist:vmkernel.log:
YYYY-MM-DDTHH:MM:SS cpu#:#######)WARNING: NMP: nmp_PathDetermineFailure:####: Cmd (#x#a) PDL error (#x#/#x##/#x#) - path vmhba#:C#:T#:L# device naa.##ccf#####b###dc##############d# - triggering path failoverYYYY-MM-DDTHH:MM:SS cpu#:#######)WARNING: VMW_SATP_ALUA: satp_alua_getTargetPortInfo:173: Could not find relative target port ID for path "vmhba#:C#:T#:L#" - Not found (#########)YYYY-MM-DDTHH:MM:SS cpu#:#######)WARNING: NMP: nmpCompleteRetryForPath:###: Retry cmd #x#a (#x##ba#f#a####) to dev "naa.##ccf#####b###dc##############d#" failed on path "vmhba#:C#:T#:L#" H:#x# D:#x# P:#x# Valid sense data: #x# #x## #x#.
Prior to the reboot, ignored the progress from the ESXi (inventory) page of the vCenter or host UI as the operations would be inaccurate at the time.