An ESXi host with one or more LUNs in an All Paths Down (APD) condition may become not manageable in vCenter server and may experience these symptoms:
The ESXi host appears as Disconnected or Not Responding in the vCenter Server inventory
Virtual machines using the LUNs experiencing the APD may become unresponsive
var/log/vobd.log there is an event for "Device has entered APD state."YYYY-MM-DDTHH:MM:SS.255Z: [APDCorrelator] 15992267920301us: [esx.problem.storage.apd.start] Device or filesystem with identifier [########-########] has entered the All Paths Down state.YYYY-MM-DDTHH:MM:SS.764Z: [APDCorrelator] 15992274428660us: [esx.clear.storage.apd.exit] Device or filesystem with identifier [########-########] has exited the All Paths Down state.
Where: ########-######## represents the identifier of the datastore. In this example, the identifier is for an NFS datastore, and the details of the datastore can be found in the output of the "esxcfg-info | less" command by searching for that identifier.
VMware ESXi 7.x
VMware ESXi 8.x
If datastores that are needed by an ESXi host are no longer accessible because all data paths between the ESXi host and the datastore are no longer passing packets, then the ESXi host may appear as "Not Responding" when viewed from vCenter server.
If the storage used is iSCSI, A common cause of persistent or intermittent APD conditions is a misconfigured or non-standardized iSCSI network topology. If iSCSI storage traffic is not isolated to a dedicated Layer 2 path and is instead routed through a default gateway or firewall, it is subjected to routing delays, packet inspection, and state timeouts. Because iSCSI is highly sensitive to latency, these network delays trigger APD events, causing the host daemon (hostd) to become unresponsive.
/etc/init.d/hostd restart/etc/init.d/vpxa restartesxcli storage core adapter rescan --all