If a user has their Outlook setup to store the personal PST files on a network share. This causes severe latency with the DLP Agent.
Network stored .PST files are not recommended by Microsoft (https://support.microsoft.com/en-us/kb/297019) and is not supported by DLP. If users are doing this and changing to locally stored PST files is not an option then it is highly recommended that we remove the Outlook channel and remove Microsoft Outlook from Application File Access as these events will trigger as copy to network share and thus exclusions cannot be applied to them. This causes every syncing action to be analyzed and cripples performance.