This article details the System Requirements for PGP Desktop 10.0 for Windows.
Note: The above operating systems are supported only when all of the latest hot fixes and security patches from Microsoft have been applied.
PGP Whole Disk Encryption (PGP WDE)
PGP Whole Disk Encryption (WDE) is supported on all client versions above as well as the following Windows Server versions:
For additional system requirements and best practices information on using PGP WDE on Windows Server systems, click here.