In the Windows Application event log, an error message indicates that Symantec Mail Security for Microsoft Exchange was unable to send an attachment to the "Quarantine Server." An example:
There is a communication issue between the Exchange server upon which SMSMSE is installed and the Quarantine Server.
Resolve any networking issues between the SMSMSE server and the Quarantine Server.
To troubleshoot the connection to the Quarantine server follow these steps