Helpdesk 6 does not generally send out email with the Helpdesk server's URL in it. If so, a custom email template has been created by the user to do this. This would need to be identified and the URL changed to reflect any actual change to the Helpdesk's URL as this is not automatic but is hardcoded into the template's HTML code.
The way that this works is as follows:
Depending on how much the user is aware of how this process works in their environment, more or less of the following instructions will need to be followed to find and change the email template involved.
Where can I find technical support for the discontinued Altiris Helpdesk 6 product?