To block any executables from pcAnywhere in the Windows 2008 Domain Controller, complete the following steps.
Alternatively, this could be done using Applocker. If you want to use Applocker, refer to Microsoft for documentation.
These changes affect users who logout and login again after the above steps are completed. When they attempt to run pcAnywhere, they will receive the following message, “This program is blocked by group policy. For more information, contact your system administrator.”