ESXi host fails to sync with NTP server.
A packet trace doesn't show any NTP traffic being put on the wire from the ESXi host.
ntpq -c associations reports a condition of reject:
ESXi
The host is running in an unsupported configuration where multiple vmk adapters are configured on the same subnet and the default gateway is tied to the wrong vmk adapter.
[root@esxihost:~] esxcfg-vmknic -l
Interface Port Group/DVPort/Opaque Network IP Family IP Address Netmask Broadcast MAC Address
vmk0 Management Network IPv4 X.X.1.10 255.255.255.0 X.X.1.255 xx:xx:xx:xx
vmk1 vMotion IPv4 X.X.1.11 255.255.255.0 X.X.1.255 xx:xx:xx:xx
[root@esxihost:~] esxcfg-route -l
Network Netmask Gateway Details about the destination Interface Details about the vmk port
X.X.X.10 255.255.255.0 Local Subnet
X.X.X.11 255.255.255.0 Local Subnet
default 0.0.0.0 XX.XX.1.1 vmk1 Port_Group=vMotion --> MTU=1500
Change your configuration to have only a single vmk on a subnet, and be sure the default gateway is assigned to the vmk0 interface.
Once the default gateway is using vmk0 NTP will connect.
https://knowledge.broadcom.com/external/article?articleId=318546 - Explains that having two vmk adapters on the same subnet is an unsupported configuration with few exceptions.
Japanese KB: NTP が condition Reject で同期に失敗する