SMS Self-Signed Certificate is used during communication with IOFilter VP and SMS Self-Signed and vp certificate. Deleting sms_self_signed will make all Vasa Provider offline on restart of SPS service and customer needs to unregister and re-register them again.
Unregister and re-register IOFilters by using the script available in this KB Article - Resolving IOFilter disconnected/offline post upgrade to 7.0u2