Powering on a virtual machine fails.
A virtual machine fails which leads to becoming in an orphaned state.
A virtual machine backup job fails.
In the /var/log/vmkernel.log file of the ESXi host where the virtual machine is running, you see entries similar to:
Device naa.xxxxxxxxxxxx with a VMFS partition is marked perennially reserved. This is not supported and may lead to data loss.
This issue occurs due to:
esxcli storage core device list -d naa.id
You could execute this command to list out all the devices along with their reservation status:
Note: The KB above is not applicable to Clustered VMDK. VMware recommends settings perennially reserved flag on Clustered VMDK. Refer to the KB 1016106 for more details.