When attempting to use the Microsoft Project Interface with PPM, users are getting a 'Run-time error 453' followed by a second error: 'Can't find DLL entry point SetCurrentDirectoryA in kernel32'
The macros used by the MSP Interface are being blocked by an antivirus software, such as Cylance.
One way to tell if this is the case is to check the application logs in the Windows Event Viewer. There will be an entry indicating the following:
'A potentially malicious Macro script was Blocked by policy'
Release: CODFSS99000-15.4.1-PPM SAAS FedRAMP-Sandbox-Small Environment
An exception would need to be created for the antivirus software to allow the macros. The MSP Interface will work without error after this.