If you are unable to Run any of your functions from within the Plex Generate and Build window, you may be receiving the following error from the Visual studio Just-In-Time Debugger window:
"An unhandled win32 exception occurred in Obexe32.exe".
Your .bld file may be corrupted. Try deleting the .bld file and allow Plex to recreate it. You will then need to re-specify your Generate and Build options.