Network traffic originating from an NSX Edge Virtual Machine (VM) is dropped at the vSphere Distributed Switch (DVS) portgroup level and fails to traverse the host physical uplink.
VMware NSX
Identified that the packet loss at the DVS layer was caused by a settings conflict on the portgroup. Specifically, enabling both MAC Address Change (under Security policy) and MAC Learning at the same time causes the switch to drop frames during processing.
Note: If this configuration is specific to a third-party vendor, we recommend consulting with the respective vendor to review their official guidance and supported limits before proceeding with the setup.
For more information refer KB- https://knowledge.broadcom.com/external/article/438391