The primary product affected is VMware vSphere ESXi within the Networking component.
vmkping) show 100% packet loss when using large payloads, despite the hosts being reachable via standard ICMP pings.The issues are caused by a network-layer MTU configuration mismatch on the Management Network (vmk0).
In this scenario, one host is configured with a standard MTU of 1500, while the peer host is configured for Jumbo Frames (9000). If the underlying physical network infrastructure does not consistently support Jumbo Frames across the entire path, packets exceeding 1500 bytes are dropped, leading to heartbeat loss and migration failures.
To resolve the configuration mismatch and stabilize host connectivity, align the MTU settings across all ESXi hosts and the physical network.
Prerequisites
Steps to Align MTU to Standard (1500)
Verification via Command Line
Perform a size-specific ping from the ESXi shell to verify the path:
vmkping -I vmk0 -d -s 1472 <destination_IP>vmkping -I vmk0 -d -s 8972 <destination_IP>Alternative Solutions
If Jumbo Frames are required for the environment but the physical network is not yet fully configured:
Related KB: KB 318647 ESXi host disconnects intermittently from vCenter Server
Related KB: KB 313061 Testing jumbo frame pings from ESXi over the network
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