This issue typically occurs after migrating other high-traffic virtual machines (such as HTTP Proxies) onto the same ESXi host and VLAN where the standby appliance reside.
Vmware vSphere ESXi
Promiscuous Mode set to "Accept"To stop unwanted traffic from being mirrored into the standby Citrix (NetScaler) load balancer virtual machine, adjust Promiscuous Mode Settings
For more architectural details and in-depth information regarding virtual switch behavior and security policies (including Promiscuous Mode), refer to KB 324553.