This is a known issue.
Workaround
Verify that IPv6 RPF Failure Drops counter is increasing on ESXi host.
- SSH to the ESXi host
- Run nsxcli
- Run get logical-routers
- Run get logical-router <Router-ID> interfaces for each logical-routers ID (VDR UUID) and find the interface ID (LIF UUID) that the segment is connected.
- Run get logical-router <Router-ID> interface <Interface-ID> stats and make sure IPv6 RPF Failure Drops counter is increasing.
Change the uRPF mode on the affected segment from STRICT to NONE to bypass the RPF check for return traffic.
- Log in to NSX Manager.
- Navigate to Networking > Segments.
- Edit the segment connected to the impacted VMs.
- Expand Additional Settings.
- Change uRPF mode from STRICT to NONE.
- Click Save.