Zero Prevalence Pruning is enabled, but a majority of the files in the environment are not eligible due to being included in the Antibodies_Lookup table
When the Carbon Black File Reputation (CDC) is disconnected, deactivated, or unconfigured, files queue up in the dbo.antibodies_lookup table awaiting a reputation re-check from the App Control server. Because they are stuck in this pending state, they bypass the pruning process and cannot be purged. This is being investigated in CRE-23992.
See Check CDC Status and Connectivity.
Important Note: Only proceed with this option if you do not plan to fix the CDC connection issue. If you want CDC reputation lookups to function properly in the future, you must revert these changes.
If you encounter this issue, please open a support case with Broadcom and request that it be associated with CRE-23992.