The DLP Enforce Console reports the following system event:
Intermittent failures are observed where some notifications are delivered successfully while others fail with the 421 response code.
The upstream SMTP relay is returning a 421 SMTP response code. This typically indicates that the relay has reached its maximum allowed number of simultaneous connections or is rate-limiting the Enforce server's IP address.
Because the DLP Enforce server does not currently have a built-in retry mechanism for failed Response Rule notifications, any connection rejected by the relay results in a permanent failure for that specific notification attempt
Work with your email or security team to adjust the settings on the SMTP gateway (e.g., Proofpoint):
If the relay limits cannot be adjusted, reduce the number of concurrent SMTP sessions initiated by Enforce:
If the failure involves sender notifications for blocked emails, consider using the Block SMTP Message response rule instead of Send Email Notification.
Request to be added as an endorser for ISFR-2898, which seeks to add a configurable retry interval for failed email notifications sent via Enforce response rules.