In VMware DHCP clients successfully obtain an initial IP address via broadcast but fail to renew the lease. The renewal process, which utilizes unicast communication, is blocked at the NSX security layer. This results in the client failing to receive the DHCP ACK (Acknowledgment), leading to lease expiration and loss of network connectivity.
The default Segment Security Profile has the "DHCP Server Block" enabled. This security feature is designed to prevent rogue DHCP servers by dropping any DHCP server traffic (specifically unicast ACKs) that does not originate from a trusted source defined within the segment's security configuration.
See Product documention for more details around Segment - Create a Segment Security Segment Profile