VMWare NSX 4.x
The issue is caused by a Path MTU (PMTU) mismatch occurring at the physical perimeter.
Specifically, a physical firewall on the northbound data path was not configured for Jumbo Frames, leaving its interface MTU set to the default of 1500 bytes. Because the Geneve-encapsulated packets or large routed frames originating from the NSX environment exceeded this 1500-byte limit, the firewall dropped or fragmented the traffic.
To resolve this issue, the physical network path must be aligned to support the required MTU size.
Engage the Firewall Vendor/Network Team: Work with the physical firewall administrator or vendor to increase the interface MTU (typically to 9000 for Jumbo Frames) to ensure consistency across the entire physical data path.
Further Troubleshooting: For detailed steps on verifying and troubleshooting MTU mismatches and fragmentation within the NSX fabric, refer to official VMware Knowledge Base: https://knowledge.broadcom.com/external/article/374882