VMware NSX
The default response timeout value of application profile is 60 seconds
The default idle timeout value of application profile is 1800 seconds
and the below document can be referred to set the same in NSX ui:
The maximum value for response timeout of application profile is 2147483647.
If the response timeout value is increased to bigger value, the connection number might reach the maximum connection limit for each Load Balancer and the new connections will be rejected based on that.