vSphere Replication 9.x
This issue is caused by checksum and read errors on the VMDK that prevent vSphere Replication (VR) from accessing the required disk blocks, and their occurrence across multiple datastores indicates underlying corruption or unreadable sectors within the VMDK.
2025-11-12T07:21:49.143Z Wa (180) vmkwarning: cpu3:2098075) WARNING: Hbr: 1528: Failed to read checksum data (DiskID=RDID-########-175d-####-853b-###########(offset15100870656) (extentSize=8192) (count=8): I/0 error
Perform a VMDK integrity check and repair, and if corruption is confirmed, restore the VM from a known good backup or snapshot before reconfiguring replication. If no valid backup is available, consider cloning the VM or creating a new VMDK and migrating the data at the OS or application level to ensure it resides on a healthy disk.