VMware NSX
The vusb0 adapter is created automatically by the vendor-provided custom ISO used to install or upgrade ESXi. It enables a secure connection to the physical server console directly from the host operating system.
As the vusb0 adapter is reported to NSX as down, the ESXi hosts are set to Degraded state.
A downed vmnic# is either having a cable issue or a adapter which shouldn't be in use.
To resolve the degraded host state in NSX and successfully pass the SDDC upgrade pre-check, perform either options as appropriate:
Verification
After disabling the vusb0 adapters or reconnecting vmnics, verify that the ESXi host status displays as "Up" in the NSX UI.
Run the NSX upgrade pre-check from SDDC Manager
For more information regarding vusb0, please refer article: ESXi creates standard switch vSwitchBMC with uplink vusb0 automatically after upgrading to 8.0.3 version