VMware NSX
The root cause was identified as an MTU (Maximum Transmission Unit) mismatch between the NSX overlay network and the underlying physical network fabric, specifically on the physical NICs of the NSX Edge cluster hosts.
To resolve this issue, set MTU on the physical NICs of the NSX Edge cluster hosts to 9000 or higher. This enables support for jumbo frames on the physical network.
Note:- Setting the physical network's MTU to 9000 ensures that the underlay network is aligned with the requirements of the NSX overlay. This configuration allows the larger, encapsulated packets to pass through the physical infrastructure without being fragmented or dropped, thereby re-establishing reliable end-to-end communication for all traffic types. Following this change.