Regarding the impact of the following fix in VMware ESXi 8.0 Update 3g Release Notes
PR 3421841: ESXi fails to boot on systems with more than 512 logical CPUs in one NUMA node
Prior to ESXi 8.0 Update 8g, ESXi fails to boot on systems with more than 512 logical processors, or hyperthreads, in one NUMA node. Such systems are very unusual, but configuring the NUMA Nodes per Socket BIOS setting to 0 (NPS0) and deactivating the CCX as NUMA Domain on AMD system can cause all logical processors to be in a single NUMA node.
This issue is resolved in this release.
ESXi 8.0 Update 3g
This fix addresses the hardware configuration (NUMA configuration) that was causing startup failures. Therefore, it is expected that no adverse impact will result from this fix.