How to use Amazon AWS S3 bucket as a datastore to mount directly to the ESXi host.
VMware vSphere ESXi 7.0.x
ESXi does not natively support using an AWS S3 bucket as a datastore. However, you can integrate an AWS S3 bucket by deploying an AWS Storage Gateway, which presents the S3 bucket in a supported format such as NFS that ESXi can mount as a datastore.
For setup and configuration, it’s recommended to engage the vendor for assistance with Amazon S3 File Gateway.
Below are some articles for reference :
https://docs.aws.amazon.com/filegateway/latest/files3/what-is-file-s3.html