While migrating the vSphere replication appliance between hosts, we would see a warning "This entity is managed by solution VR Management. It is not recommended to modify it directly".
vSphere replication 8.8
vSphere replication 9.x
The warning would show up as the VRMS appliance is managed appliance and not recommended any changes on the hardware and settings.
The warning can be ignored and can migrate the VM between hosts. Avoid any hardware and configuration changes on the appliance.