vmkping -d -s 8972 fails between endpoints, while vmkping -d -s 1472 succeeds.VMware NSX
Physical network infrastructure is not configured to support the MTU size defined on virtual switches or VMkernel adapters. End-to-End MTU is to be consistent and set to allow jumbo frames.
pktcap-uw on the ESXi host to verify large frame arrival at the physical NIC (vmnic).vmkping with higher MTU size shows success.Refer below documents for more information
Guidance to Set Maximum Transmission Unit
Enabling Jumbo Frames on virtual switches