NFS datastores have become inaccessible or no longer visible in the vCenter.
vCenter Server
ESXi
NFS
Permissions for the volume (NFS export) that is backing the NFS Datastores are not set correctly.
Over a SSH session to the host, we may see that the datastores are mounted and accessible.
We may navigate into the NFS Datastore however, when attempt to list files (command ls), it returns Permission Denied
Log file /var/log/esxupdate.log file on the ESXi hosts will report the these missing datastores:[####-##-##T##:##:##] esxupdate: 2101793: esxupdate: ERROR: An esxupdate error exception was caught:[####-##-##T##:##:##] esxupdate: 2101793: esxupdate: ERROR: esxutils.EsxcliError: Errors:[####-##-##T##:##:##] esxupdate: 2101793: esxupdate: ERROR: Error getting data for filesystem on '/vmfs/volumes/<datastore>': Cannot open volume: /vmfs/volumes/<datastore>, skipping.[####-##-##T##:##:##] esxupdate: 2101793: esxupdate: ERROR: esximage.Errors.InstallationError: Failed to query file system stats: Errors:[####-##-##T##:##:##] esxupdate: 2101793: esxupdate: ERROR: Error getting data for filesystem on '/vmfs/volumes/<datastore>': Cannot open volume: /vmfs/volumes/<datastore>, skipping.
ESXi will need read, write and execute permissions on the volume (NFS export) that is backing the NFS Datastores.
Review permissions for the affected volumes and correct them.
Then, follow steps from the article Remounting a disconnected NFS datastore from the ESXi command line