Below is the blank output observed on the guest operating system when the command to identify the disk serial number was executed.
VMware vSphere 7.x
VMware vSphere 8.x
If the disk.enableUUID parameter is set to true on the vmx, the guest operating system should be able to retrieve the disk serial number without any issues, as this information is stored in the VMDK descriptor file. Unless the UUID within the VMDK is in an incorrect format, there should be no blocking issue from the VMware side.