<Time-stamp> <NSX-Manager-hostname> kernel - - - [588132.585048] watchdog: BUG: soft lockup - CPU#20 stuck for 10s! [Log4j2-TF-1-Asy:8284]
<Time-stamp> <NSX-Manager-hostname> kernel - - - [588132.585051] watchdog: BUG: soft lockup - CPU#6 stuck for 9s!
High CPU usage on the ESXi host where the NSX Manager VM is running.
The NSX Manager functionality can be restored by moving the VM to a different, healthy host and rebooting it. Verify the original host is healthy and not overprovisioned or over-utilized before moving any NSX VM back to it.
Note, that the snapshots of NSX Manager Appliance VMs should not be taken as explained in the following doc Disable Snapshots on an NSX Appliance. However, because the CPU lockup state can also come about due to snapshot quiesce actions, make sure that no snapshots are present for the NSX manager VMs.
Refer also to the vSphere ESXi article, Error: "kernel: BUG: soft lockup - CPU#Y stuck for Xs" within VM, regarding the same condition for VMs generally, not specific to NSX environments.