1.) Put Host in Maintenance Mode and reboot it (if not already done)
2.) If the issue persists after reboot, reach out to your Storage Team/Vendor to have the LUN/Volume checked on whether it is still mapped
3.) If it is still mapped: Have the Storage Team/Vendor unmap the LUN/Volume from the Array
5.) Evaluate whether the Datastore is still showing as described in the section "Issue/Introduction"