You see some long document opening times, in excess of several minutes, on endpoint machines that just got DLP installed.
The Procmon log has some entries that indicate AppSense is being constantly invoked while Word is being opened.
C:\Program Files\AppSense
C:\Program Files\AppSense\Environment Manager
C:\Program Files\Microsoft Officeoot\vfs\ProgramFilesX64\AppSense
C:\Program Files\AppSense\Environment Manager\Agent\EmLoader.dll
C:\Program Files\Microsoft Officeoot\vfs\ProgramFilesX64\AppSense\Environment Manager\Agent\EmLoader.dll
AppSense Environment Manager or Ivanti Environment Manager, owned by Landesk, is a desktop management software used for personalizing desktop experiences.
With both AppSense and the DLP agent running, the endpoint suffers slowness when opening files.
Exclude AppSense from DLP monitoring.