After breaking multiple vCenter's Enhanced Link Mode (ELM), you will be unable to connect to the Compute Manager in NSX.
VMware NSX 4+
VMware NSX-T 3+
When a cross-domain repoint (changed the SSO domain) is performed, you can experience a known bug in the process.
This is not an NSX issue, for resolution, please refer to the KB:
VPXD.CFG file is not updating solution user with the new SSO domain name