The ESXi Host Logs are showing Latencies relation to the devices being accessed. Examples:
/var/log/vmkernel.log:
2025-03-20T19:03:05.361Z cpu81:2098508)WARNING: ScsiDeviceIO: 1513: Device ######## performance has deteriorated. I/O latency increased from average value of 1019 microseconds to 95139 microseconds.
/var/log/vmkwarning.log:
2025-03-20T19:04:40.833Z cpu49:2098506)WARNING: ScsiDeviceIO: 1513: Device ######## performance has deteriorated. I/O latency increased from average value of 995 microseconds to 43345 microseconds.
If the LUNs are underperforming were the VMs reside this results in VMs experiencing latency.