/var/run/log/vmkernel.log on the affected ESXi, memory controller errors are observed.YYYY-MM-DD THH:MM:SS cpu3:#######)MCA: 209: CE Intr G0 ################# ###### ###### ######### Memory Controller Read Error on Channel 0.MCA bank number: 0x7/var/run/log/vmkernel.logYYYY-MM-DD THH:MM:SS Lost access to volume <volume UUID> due to connectivity issues. Recovery attempt is in progress and outcome will be reported shortly.YYYY-MM-DD THH:MM:SS [msg.hbacommon.locklost] The lock protecting '<vm-name>.vmdk' has been lost, possibly due to underlying storage issues. PANIC: Exiting because of failed disk operation.VMware vSphere ESXi 7.x
A memory controller failure may cause severe storage I/O exceptions, leading directly to an ESXi host instability event or system termination.
Please contact the hardware vendor for further investigation into the memory issue.
For further explanation of MCE errors, please refer to KB:
ESXi Host Becomes Unresponsive Due to Memory Controller Errors Leading to Storage I/O Issues