Creating a new datastore on an iSCSI LUN fails with error "Cannot change the host configuration. Failed to update disk partition for ..."
Same error is seen when trying to create a datastore from the host client.
Environment
VMware vSphere ESXi with iscsi storage connected
Cause
ISCSI network misconfiguration, such as MTU mismatch between the esxi hosts, physical switches and the storage array is the cause for the failure.
Resolution
If jumbo frames are used for iscsi connectivity, ensure the esxi hosts, switches and storage array all have jumbo frames (MTU 9000) set. Refer KB318937
To test the network connectivity between esxi and storage array with MTU 9000 refer KB311055