A datastore is inaccessible
A storage fault may have occurred and may already have been remediated (e.g. a faulty device has been replaced).
/var/log/vmkernel.log has logging similar to:
cpu4:2100166 opID=3daf56db)Vol3: 2204: Could not open device 'naa.################################1' for volume open: Not found
cpu4:2100166 opID=3daf56db)WARNING: ScsiDeviceIO: 12155: READ CAPACITY on device "naa.################################" from Plugin "HPP" failed. I/O error
cpu4:2100166 opID=3daf56db)WARNING: ScsiDeviceIO: 12155: READ CAPACITY on device "naa.################################" from Plugin "HPP" failed. I/O error
cpu4:2100166 opID=3daf56db)LVM: 6444: Could not open device naa.################################:1, vol [########-########-####-############, ########-########-####-############, 1]: No such target on adapter
The partition table is unreadable:
Device: /vmfs/devices/disks/naa.################################
Partition table:
Error: Error opening /dev/disks/naa.################################5: No such device
Unable to get device /vmfs/devices/disks/naa.################################
VMware vSphere 7.0.x
VMware vSphere 8.0.x
There is a basic access issue to the device (I/O error).
In some cases, the storage level issue may be resolved, but the errors persists at ESXi level. In that case, a storage rescan on the host or a host reboot may restore access to the device/datastore.
If issues persist after a storage rescan and host reboot, engage your storage vendor support to investigate further.