After a Wordpress admin has authenticated via SSO Agent, and is using Wordpress, the AJAX called are intercepted by the agent.
Backend Application: Wordpress
SSO/Siteminder Agent: R12.Sp3 Cr12 and newer
Apache Reverse Proxy: 2.2
1. Configure the ACO setting OverlookSessionForUrls = /wp-admin/admin-ajax.php
For further information regarding this configuration and related agent configuration objects please review the documentation linked below.