Even in perfect conditions with low CPU usage (<50%) on the Edge Virtual Machine, an NSX Edge Virtual Machine cannot achieve receive rate packet loss of less than 0.001%.
Calculating receive rate loss:
Edge> get physical-port fp-eth1 stats
Physical Port Stats
NAME : fp-eth1
RX_BYTES : 2992669382
RX_ERRORS : 0
RX_MISSES : 25296
RX_NOMBUFS : 0
RX_PACKETS : 3613777910
TX_BYTES : 1288975412
TX_DROPS : 0
TX_ERRORS : 0
TX_PACKETS : 13924459
(25296/3613777910) x 100 = 0.0007%
VMware NSX-T 3.x
VMware NSX 4.x
This is due to the fundamental nature of the Edge being a virtualized entity on shared infrastructure and the requirement to be scheduled on ESXi CPUs.
If there is a requirement for the environment to achieve sub 0.001% packet loss, Broadcom recommends to deploy a Bare Metal Edge.