Check the logs on affected transport node
nsx-syslog.log:
2024-11-08T09:37:58.629Z nsx-prozy[3594881]: NSX 3594881 - [nsx@6878 comp="nsx-esx" subcomp="nsxproxy" s2comp="nsx-net" tid="3594908" level="WARNING"] StreancConnection[1197 connecting to ssl://<nsxmgrip>:1235 sid:1197] Couldn`t connect to 'ssl://x.x.x.x:1235' (error: 110-Connection timed out)
2024-11-08T09:37:58.629z nsx-proxy[3594881]: NSX 3594881 - [nsx@6876 comp="nsx-esx" subcomp="nsx-proxy" s2compu="nsx-net" tid="3594908" level="WARNING"] StreamConnection[1197 Error to ssl://<nsxmgrip>:1235 sid-1] Error 110-Connection timed out
VMware NSX