NIC driver update to 4.22.73.1006 and firmware version update to 16.35.3502 causes both VMNICs to not come UP with EDP (Enhanced Data Path) enabled and LAG configured.
The firmware has also been downgraded to 16.34.1002 and tested with 4.22.73.1006 but links do not come UP. But both VMNICs come UP in standard mode (without EDP enabled).
NSX : 3.0.2
Installed Firmware : 16.35.3502
Installed Driver : 4.22.73.1006
ESXi : VMware ESXi Version: 7.0.3 Build: 22348816
Latest Mellanox driver nmlx5_core 4.22.73.1006 on ESXi 7.0U3 is certified to work with nsx build #18504668 (VMware NSX-T Data Center 3.1.3.1) and above.
This issue is fixed in NSX version 3.1.3.1 and above
Upgrade NSX to latest releases to work with latest Mellanox driver firmware versions for switches with EDP enabled