Automatic replies, like out of office messages, processed through Network Prevent for Email DLP servers are not delivered to external recipients. You see the below error in the NDR (Non-Delivery Report):
550 5.7.26 Your email has been blocked because the sender is unauthenticated
15.X
16.0
In the RequestProcessor logs you see that e-mail was processed correctly to the downstream MTA and the sender field is empty.
INFO: (SMTP_MESSAGE.1300) Message complete (tid=27 cid=Upstream-fdcb6c75-dbeb-47b1-9338-faa603f58a3e message_id=<xxx@xxx> dlp_id=19068269d05 size=2,209 sender=<> recipient_count=1 disposition=PASS code=250 estatus=<>text=<2.0.0 40354n8aat-1 Message accepted for delivery> rtime=0.06s dtime=0.03s mtime=0.48s)
The RequestProcessor logs shows empty sender field which indicates that the upstream MTA did not included sender information in the message processed through NPE server. Some e-mail services might not accept messages without proper sender field and this has be fixed on upstream MTA host.