Make sure the persistent method is configured correctly:
"The available persistence methods for TCP are sourceip, and msrdp"
"The available persistence method for UDP is sourceip"
"The available persistence methods for HTTP are sourceip and cookie"
"The available persistence methods for HTTPS are sourceip, and cookie when ssl passthrough is disabled"
"The available persistence methods for HTTPS are sourceip, and sslsessionid when ssl passthrough is enabled"