To understand the cause that led to the exhaustion of a module's heap it is important to collect essential diagnostic information from the ESXi host. Open a support request with VMware GSS.
To work around this issue, reboot the ESXi host to reinitialize all the heaps in the system. But, VMware recommends to collect essential diagnostic information including the live memory dump of ESXi host with the help of VMware GS before rebooting the host.
Note: If you see this issue in an ESXi 5.5 host and the heap that ran out of space is 'seSparse', then install VMware ESXi 5.5, Patch ESXi550-201312401-BG to resolve this issue. For more information , see
VMware ESXi 5.5, Patch ESXi550-201312401-BG: Updates esx-base(2063788).