Symptoms:
2015-07-29T01:55:16.368Z| vmx| I120: FileIOErrno2Result: Unexpected errno=87, Too many users2015-07-29T01:55:16.368Z| vmx| I120: AIOGNRC: Failed to open '/vmfs/volumes/556668a8-#########-####-##########fe/xxxx/xxxx-rdmp.vmdk' : Too many users (570002) (0x4013).2015-07-29T01:55:16.368Z| vmx| I120: OBJLIB-FILEBE : FileBEOpen: can't open '/vmfs/volumes/556668a8-#########-####-##########fe/xxxx/xxxx-rdmp.vmdk' : Too many users (5701636).2015-07-29T01:55:16.368Z| vmx| I120: DISKLIB-VMFS : "/vmfs/volumes/556668a8-#########-####-##########fe/xxxx/xxxx-rdmp.vmdk" : failed to open (Too many users): ObjLib_Open failed. Type 102015-07-29T01:55:16.368Z| vmx| I120: DISKLIB-LINK : "/vmfs/volumes/556668a8-#########-####-##########fe/xxxx/xxxx.vmdk" : failed to open (Too many users).2015-07-29T01:55:16.368Z| vmx| I120: DISKLIB-CHAIN : "/vmfs/volumes/556668a8-#########-####-##########fe/xxxx/xxxx.vmdk" : failed to open (Too many users).2015-07-29T01:55:16.368Z| vmx| I120: DISKLIB-LIB : Failed to open '/vmfs/volumes/556668a8-#########-####-##########fe/xxxx/xxxx.vmdk' with flags 0x4a Too many users (5701641).2015-07-29T01:55:16.368Z| vmx| I120: DISK: Cannot open disk "/vmfs/volumes/556668a8-#########-####-##########fe/xxxx/xxxx.vmdk": Too many users (5701641).2015-07-29T01:55:16.368Z| Worker#0| I120: FileIOErrno2Result: Unexpected errno=87, Too many users2015-07-29T01:55:16.369Z| Worker#0| I120: AIOGNRC: Failed to open '/vmfs/volumes/556668a8-#########-####-##########fe/xxxx/xxxx_1-rdmp.vmdk' : Too many users (570002) (0x4013).2015-07-29T01:55:16.369Z| Worker#0| I120: OBJLIB-FILEBE : FileBEOpen: can't open '/vmfs/volumes/556668a8-#########-####-##########fe/xxxx/xxxx_1-rdmp.vmdk' : Too many users (5701636).Note: The preceding log excerpts are examples. Date, time, and environmental variables may vary depending on your environment.
This is a known issue.
To work around this issue, share write access to the resources with no more than 8 for 4.x and 32 for 5.x ESXi/ESX hosts at a time.For more information about the virtual machine log file location, see Locating virtual machine log files on an ESXi/ESX host (1007805).
Locating virtual machine log files on an ESXi/ESX host
Enabling or disabling simultaneous write protection provided by VMFS using the multi-writer flag
VMRC becomes unresponsive when attempting to mount an ISO file that is mounted to too many virtual machines