Symptoms:
To resolve the issue provide Cloud Director with a vCenter user with sufficient privileges, including the Right Certificates > Manage certificates.
Typically Cloud Director would be provided with a vCenter user using an Administrator Role, for more information see Attach a vCenter Server Instance Alone or Together with an NSX Manager Instance.
To verify outside of Cloud Director if the vCenter user has sufficient rights we can use curl to query the vCenter API.
If the user returns an error despite having the correct rights ensure that the rights are applied to the user either at the vCenter level in inventory or at the global level in vCenter -> Administration -> Global Permissions.
For more information on trusting vCenter Server certificates in Cloud Director see the knowledge base article here, vCenter Server, ESXi and/or NSX are disconnected after a Cloud Director 10.1, 10.3 or 10.4 upgrade (78885).