The issue was triggered by a change in ESXi 5.5 p10, 5.5 ep11, 6.0 p04, 6.0 U3 and, 6.5 GA in which ESXi disables the Intel IOMMU's (aka VT-d) interrupt remapper functionality. In HPE ProLiant Gen8 servers, this change causes PCI errors which result in the platform generating an NMI and causing the ESXi host to fail with a purple diagnostic screen.
HPE has identified the cause of the issue on the HPE ProLiant DL560 Gen8 server and HPE ProLiant DL380p Gen8 server as high performing, low-latency PCIe adapters installed in slot 3 and systems under heavy load. For more information, see
HPE CUSTOMER ADVISORY.
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