openssl s_client -connect myhost:8182
" from affected, the tcp handshake happens but no TLS traffic is seen.There are many types of traffic, most notably vMotion and storage communication, which has higher throughput when passed with a Maximum Transmission Unit (MTU) setting of 9000, otherwise known as "jumbo" frames. An MTU setting of 1500 is considered a "standard" frame.
When network frame size is set to jumbo frames in an ESXi host's vmkernel NIC configuration, those frames might be dropped or fragmented by any other device that is set to only pass standard frames. Therefore the frame size setting for all devices along the network path must allow jumbo frames to pass in order for the communication to work.
Devices along the network path could be virtual switch ports, physical switch ports, switches (such as blade chassis switches) or routers, or the virtual switches, vmks, and vmnics of other ESXi hosts.
Having a higher frame size on physical hardware but not on ESXi's vmkernel NICs will not cause a problem. Standard frame packets can always pass through jumbo frame-configured devices.
Please note that you could have some vmks, vmnics and virtual switches configured to use standard frames, such as for management traffic, but also have other vmks, vmnics and virtual switches configured for jumbo frame traffic, such as for storage and vMotion.
First ensure connectivity concern is over VLAN connections, not VXLAN or GENEVE
Ensure all ESXi host MTU settings for the desired jumbo frame networks are consistently set to the same MTU size. The examples below assume an MTU of 9000.
You can do this through the vCenter Server user interface per Enabling Jumbo Frames on virtual switches. To do this through the command line interface (CLI):
# esxcfg-vswitch -l
# esxcfg-vmknic -l
# localcli network nic list
Test whether the MTU settings are the same throughout the physical network path as well
# vmkping -I vmk<x> <destination_IP> -d -s 8972
# vmkping -I vmk<x> -S vmotion <destination_IP> -d -s 8972
# vmkping -I vmk<x> <destination_IP> -d -s 1472
vmkping -I vmk<x> <destination_IP> -d -s 1473
Changing MTU settings (standard switch only)
You can do this through the vCenter Server user interface per Enabling Jumbo Frames on virtual switches. To do this through the command line interface (CLI):
# esxcfg-vswitch -m <MTU-1500_or_9000> <switchname>
# esxcfg-vmknic -m <MTU-1500_or_9000> vmk<x>
For distributed switches, please see the documentation located here: What are Jumbo Frames